PRODUCT INFORMATION
TELOMERE MULTI ACTIVATOR is a blend of Proprietary powerful herbs and nutrients that promote healthy cardiovascular, physical, immune, metabolic and neural systems. It helps maintain healthy blood pressure, blood sugar and vitality.
Supports multiple anti- aging and regenerative pathways including stem cells, Telomeres, longevity Genes, Genomic and Epigenetic stability, healthy inflammation levels, Autophagy, Vascular circulation and Stress Resistance.
The only way to lengthen telomeres is through the activation of an enzyme called Telomerase. Telomerase is an enzyme controlled by a gene that is usually turned off in most cases. When the Telomerase is activated, it resembles a molecular motor and adds new DNA onto the ends of shortened Telomeres, thus restoring cells to a healthier state.
Sourced using only the finest raw ingredients with the purity and potency your body deserves. This product is certified and manufactured in the USA, also a certificate of analysis is available for every product we produce.
TELOMERASE NOBEL PRIZE
More than 35 years ago, telomerase activity was discovered by Elizabeth H. Blackburn and Carol W. Greider. Today, this enzyme is a promising approach to curing some age-related diseases as well as cancer, but it took time for telomerase to be in the spotlight.
The existence of an enzyme, a DNA polymerase, that could elongate the ends of chromosomes or telomeres was predicted in 1984 on the basis of telomere maintenance and net telomere elongation in both ciliates and yeast1. Some fifty years before that discovery, the work of Hermann Müller and Barbara McClintock had showed the occurrence of a special structure at chromosome ends — which Müller termed the telomere — that was essential to prevent chromosomes from fusing to each other2,3. The subsequent elucidation of the structure of the DNA molecule and the understanding of the DNA replication mechanisms posed the question on how to maintain the ends of chromosomes throughout cellular and organismal generations. James D. Watson and Alexey M. Olovnikov had envisioned that the ends of linear DNA molecules, such as chromosomes, would shorten every time a cell divides, owing to the incomplete replication of the ends by the conventional polymerases, a problem termed the end replication problem. Thus, to allow for species maintenance, an enzyme must exist that would compensate for the ever-shorter telomeres associated to cell division. Such an enzyme was predicted by Elizabeth H. Blackburn and Jack W. Szostak to elongate the 3´ ends of telomeric repeats to compensate for telomere loss associated to cell division, so that in this manner the ends of chromosomes would not wear away after a few cell divisions, generating chromosomal instability.
To find such an enzyme was of potential great importance, as its telomere elongating activity or the lack thereof could explain the limited life span of normal cells, also known as the Hayflick limit4 as well as organismal aging and longevity. Such an activity could also explain the immortal nature of cancer cells and their ability to divide indefinitely.
While working at Joe Gall´s group, Blackburn had sanger-sequenced the first chromosome end from the ciliate Tetrahymena and found a gene-less repeated sequence heterogeneous in length5. Possibly, the fact that the ends of chromosomes did not harbour any gene that could explain their function decreased the enthusiasm of the scientific community but not that of Blackburn, who was convinced that such repeated DNA must somehow hold the key to aging and longevity of life.
The Nobel Prize in Physiology or Medicine 2009
Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak
“how chromosomes are protected
by telomeres and the enzyme telomerase“
This year’s Nobel Prize in Physiology or Medicine is awarded to three scientists who have solved a major problem in biology: how the chromosomes can be copied in a complete way during cell divisions and how they are protected against degradation. The Nobel Laureates have shown that the solution is to be found in the ends of the chromosomes – the telomeres – and in an enzyme that forms them – telomerase.
The long, thread-like DNA molecules that carry our genes are packed into chromosomes, the telomeres being the caps on their ends. Elizabeth Blackburn and Jack Szostak discovered that a unique DNA sequence in the telomeres protects the chromosomes from degradation. Carol Greider and Elizabeth Blackburn identified telomerase, the enzyme that makes telomere DNA. These discoveries explained how the ends of the chromosomes are protected by the telomeres and that they are built by telomerase.
If the telomeres are shortened, cells age. Conversely, if telomerase activity is high, telomere length is maintained, and cellular senescence is delayed. This is the case in cancer cells, which can be considered to have eternal life. Certain inherited diseases, in contrast, are characterized by a defective telomerase, resulting in damaged cells. The award of the Nobel Prize recognizes the discovery of a fundamental mechanism in the cell, a discovery that has stimulated the development of new therapeutic strategies.
The mysterious telomere
The chromosomes contain our genome in their DNA molecules. As early as the 1930s, Hermann Muller (Nobel Prize 1946) and Barbara McClintock (Nobel Prize 1983) had observed that the structures at the ends of the chromosomes, the so-called telomeres, seemed to prevent the chromosomes from attaching to each other. They suspected that the telomeres could have a protective role, but how they operate remained an enigma.
When scientists began to understand how genes are copied, in the 1950s, another problem presented itself. When a cell is about to divide, the DNA molecules, which contain the four bases that form the genetic code, are copied, base by base, by DNA polymerase enzymes. However, for one of the two DNA strands, a problem exists in that the very end of the strand cannot be copied. Therefore, the chromosomes should be shortened every time a cell divides – but in fact that is not usually the case (Fig 1).
Both these problems were solved when this year’s Nobel Laureates discovered how the telomere functions and found the enzyme that copies it.
Telomere DNA protects the chromosomes
In the early phase of her research career, Elizabeth Blackburn mapped DNA sequences. When studying the chromosomes of Tetrahymena, a unicellular ciliate organism, she identified a DNA sequence that was repeated several times at the ends of the chromosomes. The function of this sequence, CCCCAA, was unclear. At the same time, Jack Szostak had made the observation that a linear DNA molecule, a type of minichromosome, is rapidly degraded when introduced into yeast cells.
Blackburn presented her results at a conference in 1980. They caught Jack Szostak’s interest and he and Blackburn decided to perform an experiment that would cross the boundaries between very distant species (Fig 2). From the DNA of Tetrahymena, Blackburn isolated the CCCCAA sequence. Szostak coupled it to the minichromosomes and put them back into yeast cells. The results, which were published in 1982, were striking – the telomere DNA sequence protected the minichromosomes from degradation. As telomere DNA from one organism, Tetrahymena, protected chromosomes in an entirely different one, yeast, this demonstrated the existence of a previously unrecognized fundamental mechanism. Later on, it became evident that telomere DNA with its characteristic sequence is present in most plants and animals, from amoeba to man.
An enzyme that builds telomeres
Carol Greider, then a graduate student, and her supervisor Blackburn started to investigate if the formation of telomere DNA could be due to an unknown enzyme. On Christmas Day, 1984, Greider discovered signs of enzymatic activity in a cell extract. Greider and Blackburn named the enzyme telomerase, purified it, and showed that it consists of RNA as well as protein (Fig 3). The RNA component turned out to contain the CCCCAA sequence. It serves as the template when the telomere is built, while the protein component is required for the construction work, i.e. the enzymatic activity. Telomerase extends telomere DNA, providing a platform that enables DNA polymerases to copy the entire length of the chromosome without missing the very end portion.
Telomeres delay ageing of the cell
Scientists now began to investigate what roles the telomere might play in the cell. Szostak’s group identified yeast cells with mutations that led to a gradual shortening of the telomeres. Such cells grew poorly and eventually stopped dividing. Blackburn and her co-workers made mutations in the RNA of the telomerase and observed similar effects in Tetrahymena. In both cases, this led to premature cellular ageing – senescence. In contrast, functional telomeres instead prevent chromosomal damage and delay cellular senescence. Later on, Greider’s group showed that the senescence of human cells is also delayed by telomerase. Research in this area has been intense and it is now known that the DNA sequence in the telomere attracts proteins that form a protective cap around the fragile ends of the DNA strands.
An important piece in the puzzle – human ageing, cancer, and stem cells
These discoveries had a major impact within the scientific community. Many scientists speculated that telomere shortening could be the reason for ageing, not only in the individual cells but also in the organism as a whole. But the ageing process has turned out to be complex and it is now thought to depend on several different factors, the telomere being one of them. Research in this area remains intense.
Most normal cells do not divide frequently, therefore their chromosomes are not at risk of shortening and they do not require high telomerase activity. In contrast, cancer cells have the ability to divide infinitely and yet preserve their telomeres. How do they escape cellular senescence? One explanation became apparent with the finding that cancer cells often have increased telomerase activity. It was therefore proposed that cancer might be treated by eradicating telomerase. Several studies are underway in this area, including clinical trials evaluating vaccines directed against cells with elevated telomerase activity.
Some inherited diseases are now known to be caused by telomerase defects, including certain forms of congenital aplastic anemia, in which insufficient cell divisions in the stem cells of the bone marrow lead to severe anemia. Certain inherited diseases of the skin and the lungs are also caused by telomerase defects.
In conclusion, the discoveries by Blackburn, Greider and Szostak have added a new dimension to our understanding of the cell, shed light on disease mechanisms, and stimulated the development of potential new therapies.
Elizabeth H. Blackburn has US and Australian citizenship. She was born in 1948 in Hobart, Tasmania, Australia. After undergraduate studies at the University of Melbourne, she received her PhD in 1975 from the University of Cambridge, England, and was a postdoctoral researcher at Yale University, New Haven, USA. She was on the faculty at the University of California, Berkeley, and since 1990 has been professor of biology and physiology at the University of California, San Francisco.
Carol W. Greider is a US citizen and was born in 1961 in San Diego, California, USA. She studied at the University of California in Santa Barbara and in Berkeley, where she obtained her PhD in 1987 with Blackburn as her supervisor. After postdoctoral research at Cold Spring Harbor Laboratory, she was appointed professor in the department of molecular biology and genetics at Johns Hopkins University School of Medicine in Baltimore in 1997.
Jack W. Szostak is a US citizen. He was born in 1952 in London, UK and grew up in Canada. He studied at McGill University in Montreal and at Cornell University in Ithaca, New York, where he received his PhD in 1977. He has been at Harvard Medical School since 1979 and is currently professor of genetics at Massachusetts General Hospital in Boston. He is also affiliated with the Howard Hughes Medical Institute.
References:
Szostak JW, Blackburn EH. Cloning yeast telomeres on linear plasmid vectors. Cell 1982; 29:245-255.
Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985; 43:405-13.
Greider CW, Blackburn EH. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 1989; 337:331-7.
FORMULA COMPONENTS
VITAMINS & MINERALS
VITAMIN A:
Origin: Supplements or food sources such as animal products, such as eggs, chicken, and beef.
Also Known As: Retinol palmitate.
Overview: Vitamin A Palmitate is the ester of retinol (vitamin A) and palmitic acid and is used to help prevent or treat low levels of Vitamin A in the body. Conditions such as hyperthyroidism, diabetes, protein deficiency, liver, and pancreas problems cause low levels of Vitamin A in the body. Vitamin A Palmitate has been shown that it can have significant benefits on eye health and vision.
Common Dosage: The recommended dosage of Vitamin A is typically based on health and age.
VITAMIN C:
Origin: Supplements or food sources like citrus fruits, berries, potatoes, tomatoes, peppers, cabbage, Brussels sprouts, broccoli and spinach.
Also Known As: L-ascorbic acid, ascorbic acid, ascorbate.
Overview: Vitamin C (Ascorbic Acid) is a vitamin that cannot be manufactured by the human body and must be acquired through diets high in fruits and vegetables or outside supplementation. Vitamin C is mostly used for preventing and treating the common cold, infections such as gum disease, acne, skin infections, stomach ulcers, helps the heart, blood vessels, and drastically helps improve the human immune system.
Common Dosage: The recommended dosage of Vitamin C (Ascorbic Acid) is 1-3 grams daily.
VITAMIN D3:
Origin: Made by the skin when exposed to sunlight; it is also found in some foods and can be taken as a dietary supplement.
Also Known As: Cholecalciferol, Ergocalciferol-D2, Alfacalcidol.
Overview: Vitamin D3 is a form of vitamin D used to treat and prevent vitamin D deficiency and associated diseases, including rickets. It is also used for familial hypophosphatemia, hypoparathyroidism that is causing low blood calcium, and Fanconi syndrome. It is usually taken by mouth.
Vitamin D3 is made in the skin following UVB light exposure. It is converted in the liver to calcifediol (25-hydroxyvitamin D) which is then converted in the kidney to calcitriol (1,25-dihydroxyvitamin D). One of its actions is to increase the uptake of calcium by the intestines. It is found in food such as fish, cheese, and eggs. Certain foods such as milk have cholecalciferol added to them in some countries.
Common Dosage: 100,000 iu/g.
VITAMIN E:
Origin: Supplements or food sources including almonds, peanuts, and hazelnuts/filberts, spinach and broccoli.
Also Known As: Tocopherol.
Overview: Vitamin E is a fat-soluble vitamin that helps prevent heart disease, blocked arteries, lowering high blood pressure, giving the body healthy brain function, giving the body healthy nervous system, boosting the immune system, treating respiratory infections, and increasing physical endurance as well as increasing energy.
Common Dosage: The recommended dosage of Vitamin E is 400mg-800mg daily.
VITAMIN K:
Origin: Synthesized from chorismate, a compound produced from shikimate via the shikimate pathway. It is made by plants and is found in highest amounts in green leafy vegetables because it is directly involved in photosynthesis.
Also Known As: Phytomenadione, phylloquinone.
Overview: Vitamin K1 is the major dietary form of Vitamin K. It is is used to treat certain bleeding disorders including warfarin overdose, vitamin K deficiency, and obstructive jaundice. It is also recommended to prevent and treat hemorrhagic disease of the newborn.
Common Dosage: 2.5 to 10 mg
VITAMIN B1:
Origin: Supplements and food sources such as grains, beans, nuts, meat, asparagus, potatoes, mushrooms, romaine lettuce, spinach, tuna, green peas, sunflower seeds, tomatoes, Brussels sprouts, and eggplant.
Also Known As: Aneurine
Overview: Vitamin B1(Thiamine Mononitrate) is typically used to help with conditions of low Thiamine in the body. It aids in improving digestive problems, helping poor appetite, boosting the immune system, kidney health, increased energy, cognitive enhancement, and a positive mental attitude. It supports energy production and optimum neural functioning. It also helps maintain the integrity and viability of your cells.
Common Dosage: The recommended dosage is 5mg-30mg for mild deficiencies.
VITAMIN B2:
Origin: Food sources include eggs, green vegetables, milk and other dairy products, meat, mushrooms, and almonds.
Also known as: Riboflavin
Overview: Vitamin B2 of riboflavin is a vitamin that is naturally present in food such as eggs, green vegetables, milk and other dairy products, meat, mushrooms, and almonds. It aids in the production of red blood cells and supports cellular functions related to energy.
As a supplement it is used to prevent and treat riboflavin deficiency and prevent migraines.
Common Dosage: When used as a dietary supplement, the common dosage of riboflavin is i1.3 mg for men and 1.1 mg for women, As a treatment for migraine, the suggested dosage is 400 mg.
VITAMIN B6:
Origin: Supplements or food sources including pork poultry such as chicken or turkey, fish, bread, wholegrain cereals such as oatmeal, wheatgerm and brown rice, eggs, vegetables, and soya beans.
Also Known As: (4-formyl-5-hydroxy-6-methylpyridin-3-yl) methyl phosphate, Pyridoxal 5-phosphate, PAL-P, PLP, Vitamin B6 phosphate.
Overview: Vitamin B6(Pyridoxal-5-Phosphate) is a vitamin used for a variety of things such as boosting the immune system, eye infections, bladder infections, preventing kidney stones, allergies, reduction in excess prolactin (males), preventing eye disease, as well as increasing appetite and helping people remember dreams.
Common Dosage: The recommended dosage for Vitamin B6 is 25mg-30mg daily.
VITAMIN B9:
Origin: Folic acid is a powdered, synthetic form of vitamin B9 (folate) that has higher rates of absorption than naturally occurring folates. Vitamin B9 is an essential vitamin that the human body cannot produce on its own. The FDA requires certain foods, such as bread, crackers, and cereal, to be fortified with folic acid because of the critical role in the body.
Also known As: Folic Acid
Overview: Folic acid powder supports many important functions in the human body and is an important part of prenatal supplements. Folic acid powder also helps support cardiovascular health and may even help maintain healthy mood and support brain function.
Common Dosage: 300 to 600mcg per day.
VITAMIN B12 :
Origin: Produced in the laboratory by reducing cyanocobalamin with sodium borohydride in alkaline solution, followed by the addition of methyl iodide.
Also Known As: Mecobalamin, MeCbl, Meb12.
Overview: Methylcobalamin is a cobalamin, a form of vitamin B12. It is equivalent physiologically to vitamin B12,[3] and can be used to prevent or treat pathology arising from a lack of vitamin B12 intake (vitamin B12 deficiency).
It is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.
Common Dosage: 1 to 25 mcg per day
VITAMIN B7:
Origin: B7 is a vitamin that plays a vital role in metabolism, gene regulation, and cell signaling. It’s a type of vitamin called a co-factor, meaning it helps enzymes break down fatty acids, glucose and amino acids so your body can function properly. While biotin gained fame as a beauty booster, it does more than keep your hair, nails and skin healthy. Unlike biotin 1%, this product has no fillers and is not cut with anything else. It is a very potent and robust form of Vitamin B7.
Also known as: Biotin
Overview: Biotin is well-known for its benefits on hair, skin, and nail health and is commonly found in anti-aging creams and lotions. When taken orally, it may support healthy hair. Biotin may also help maintain healthy glucose levels and contribute to cardiovascular health. It also helps fortify the brain, support cognitive ability and mood, and promote feelings of well-being.
Supports healthy hair, skin & nails, Helps maintain healthy glucose levels, contributes to cardiovascular health, Fortifies the brain, supports cognitive ability and mood, Promotes overall health & well-being
Common Dosage: 1mg per day.
IODINE:
Origin: (As Potassium Iodine) Potassium Iodide is a form of iodine that is preferentially taken up by the thyroid gland. This product also supports the body’s normal detoxification processes, including the removal of heavy metals.
Also known as: Potassium Iodine.
Overview: Iodine is an essential nutrient that helps support healthy thyroid function.
Common Dosage: 200mcg per day
MAGNESIUM:
Origin: Magnesium oxide is a white mineral that occurs naturally when magnesium oxidizes.
Also known as: Magnesia
Overview: Magnesium oxide is commonly taken as a source of magnesium. It also supports the bones and teeth, aids digestion, and promotes bowel movements. Magnesium oxide may also help promote a healthy mood and overall sense of well-being.
Source of magnesium, Fortifies the bones & teeth, promotes bowel movements, Aids digestion, Heart healthy, Contributes to healthy mood.
Common Dosage: 400mg per day.
ZINC:
Origin: Zinc oxide powder is a form of zinc, which is an essential nutrient and trace mineral that the body requires for normal function. Zinc is the second most abundant mineral in the body behind iron. Because Zinc is not produced by the body, we must get our Zinc from our diet. Zinc oxide powder is sometimes used as an additive in foods, such as nutrition bars and breakfast cereals, to increase zinc content.
Also known as: ZINC OXIDE
Overview: Zinc oxide powder helps support immune function, the heart, skin, eyes, and oral health. It may also support male reproductive health and promote healthy mood. Supports immune function, Works to support the heart, benefits the eyes, contributes to oral health, promotes healthy mood, Helps support male reproductive health.
Common Dosage: 10 to 50mg per day
SELENIUM:
Origin: Selenium is an essential trace mineral found in soil and water. Plants and yeast naturally convert selenium into organically bound protein forms of minerals. For improved bioavailability, Healthy Origins® SelenoExcell® contains selenium in this organically bound natural food form. SelenoExcell® was the high selenium yeast used in numerous clinical trials.
Also known as: Seleno Excell
Overview: Selenium is bound to provide high biological activity. This “high selenium yeast supplement” is a potent form of selenium, providing unsurpassed cellular antioxidant support—especially for the heart and the prostate.
Common Dosage: 200mcg per day.
COPPER:
Origin: Chelated Copper features a fully reacted form of this popular amino acid chelate mineral. An essential trace mineral, copper helps maintain the health of organs and tissues. It also supports immune and nervous system health.
Also known as: Copper chelate
Overview: copper is as valuable as ever when it comes to daily nutrition. As an essential component of vital antioxidant enzymes, copper plays an important role in maintaining the health of organs and tissues throughout the body and provide a full day’s supply of this essential trace mineral.
Common Dosage: 3mg per day.
MANGANESE:
Origin: Chelated Manganese delivers an important mineral in an easily absorbable chelated form. A vital trace mineral, manganese plays a crucial role in bone and cartilage formation, and it also supports healthy thyroid and pancreatic function.
Also known as: Manganese acid chelate
Overview: Involved in many vital functions in the body, manganese plays a role in energy production, as well as normal bone formation and development. Manganese is specially bonded (chelated) with amino acids to protect mineral value and enhance absorption.
Common Dosage: 5mg per day.
CHROMIUM:
Origin: This essential nutrient plays a key role in many metabolic processes, including lipid and carbohydrate metabolism. Helps support healthy blood sugar levels already within a normal range, reduce cravings and support protein, carbohydrate and lipid metabolism, Bound to picolinic acid for improved absorption.
Also known as: Chromium Picolinate
Overview: chromium forms to support healthy glucose levels that are already within the normal range. Chromium is an essential trace mineral that works with insulin to support healthy blood glucose levels already within the normal range and plays an important role in the proper utilization of protein, fat and carbohydrates.
Common Dosage:200mcg per day.
MOLYBDENUM:
Origin: (as Molybdenum Aspartate) Molybdenum is a mineral that plays a vital role in metabolic processes in the body.
Also known as: Molybdenum Aspartate
Overview: Molybdenum is a trace element that plays important roles in maintaining overall health. It may promote optimal health of the heart, blood, and cardiovascular system. It may aid the body in building up the immune system to fight off inflammation. It is effective at promoting optimal liver health and detoxification processes.
Common Dosage: 300mcg per day.
PROPRIETARY BLEND COMPONENTS (1310 MG)
ASTRAGALUS EXTRACT POWDER:
Origin: Derived from the roots of the astragalus or Mongolian milkvetch.
Astragalus is an herb commonly used in traditional Chinese medicine to boost the immune system as well as to treat conditions such as heart disease. It is the source of a popular medicine called huang qi that the Chinese use against colds, flus and other respiratory infections.
The herb is called an adaptogen, meaning it helps protect the body from physical, mental, or emotional stress.
It is commonly available as capsules and liquid extracts. The root may also be ground into a powder, which can be brewed into teas.
Also Known As: Mongolian milkvetch
Suggested Uses:
Boosting the immune system
Potentially improving heart function
Reducing negative side effects of chemotherapy such as nausea, vomiting, and diarrhea
Controlling blood sugar levels
Improving kidney function
Improving symptoms of chronic fatigue
Improving symptoms of seasonal allergy
Common Dosage: There is no standard recommended dosage for Astragulus at the moment. However, supplements are usually taken in doses ranging from 9 to 30 grams per day.
KOREAN GINSENG EXTRACT:
Origin: Red ginseng plant.
Also Known As: Asian ginseng, Chinese ginseng, Panax Ginseng, Red Ginseng.
Overview: Korean Ginseng extract is a nutritional supplement and herbal remedy derived from the Korean red ginseng plant. Research on the health effects of red ginseng indicates that its consumption can lead to a wide variety of benefits including immune system stimulation, glucose regulation in diabetics and tumor suppression. Red Panax Ginseng also is believed to have the ability to generally improve performance, stamina, reaction time and energy level as well as promoting and supporting a feeling of optimal well-being.
Common Dosage: 200 to 400 mg daily.
LYCOPENE:
Origin: Lycopene belongs to a class of pigmented compounds called carotenoids, which also includes beta-carotene, lutein and zeaxanthin (most known for their ability to support eye health). Carotenoids are a type of antioxidant that you can get from fruits and vegetables with bright pigments—think guava, pink grapefruit, carrots, and, of course, tomatoes
Also known as: carotenoid.
Overview: Lycopene is an essential intermediate in the pathway for synthesis of the β-ionone ring-containing carotenoids such as β-carotene in plant tissues, and in most plant tissues it is present in only minor amounts.
Common dosage: 10 TO 15 MG PER DAY
N-ACETYL-CYSTEINE:
Origin: N-acetyl-L-cysteine is an easily-absorbed nutrient with potent benefits for whole body health. N-acetyl-L-cysteine also helps replenish your body’s supply of glutathione. N-acetyl-L-cysteine and glutathione have powerful antioxidant effects.
Also known as: N-acetylcysteine, NAC.
Overview: Oral NAC (or N-Acetyl-L-Cysteine) supplements encourage healthy glutathione levels—so you can stay at your best. This 600 mg N-acetyl-L-cysteine formula is easy to absorb.
As a dietary supplement, N-acetyl-L-cysteine supports comprehensive health in a variety of ways, including promoting normal liver function. NAC is a powerful antioxidant that protects cells from oxidative stress.
Common dosage: 500 to 1000mg
RESVERATROL:
Origin: May be derived from the skin of grapes, blueberries, raspberries, mulberries, and peanuts.
Also Known As: trans-Trihydroxystilbene, Stilbenetriol, trans-Resveratrol.
Overview: Resveratrol is a is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or, when the plant is under attack by pathogens such as bacteria or fungi. It is commonly used as a dietary supplement due to its antioxidant-like behavior when ingested.
Common Dosage: At the moment, there is no standard dosage for resveratrol. However, supplements on the market today contain 250 to 500 mg.
MILK THISTLE EXTRACT:
Origin: Derived from the Milk Thistle (Silybum mrianum) plant
Also Known As: Cardus marianus, Blessed milkthistle, Marian thistle, Mary thistle, Saint Mary’s thistle, Mediterranean milk thistle, Variegated thistle, Scotch thistle.
Overview: Milk Thistle Extract 80% is a compound extracted from the milk thistle plant. It contains active components called silymarin which is known for it’s a antioxidant, antiviral, and anti-inflammatory properties.
Traditionally, it is used to treat disorders of the gallbladder and liver, to promote breast milk production, to prevent and treat cancer, and to protect the liver from environmental toxins.
Common Dosage: 420 mg per day
ASHWAGANDHA:
Origin: Ashwagandha Root is formulated to support a healthy immune and stress response. Ashwagandha is a popular Ayurvedic herb to promote immune vitality. When the body is stressed, the immune and nervous systems can be depleted. Ashwagandha nourishes and restores optimal nervous and immune system health by normalizing mood and energy levels as well as overall immune function.
Overview: Ashwaganda is an “adaptogen”. Adaptogens increase resistance to the adverse effects of stress (mental, emotional, and physical). Ashwagandha promotes greater sustained levels of energy, as well as deeper levels of relaxation. Also supports an exhausted nervous system by supporting the adrenal glands that respond to stress.
Ashwagandha supports key enzyme systems related to the conversion of thyroid hormones T4 into T3, also called the ‘active thyroid hormone’, which is responsible for mood, metabolism and digestion.
COmmon dosages: 300 TO 500 MG
BACOPA MONNIERI:
Origin: Derived from the Bacopa Monnieri plant.
Also Known As: Water hyssop, Brahmi
Overview: Bacopa may support learning, memory, and may help moderate stress levels, may also provide antioxidant protection to important areas of the brain, such as the frontal cortex and striatum, and help you complete tasks in a more efficient manner.
It has been used in Ayurvedic medicine for improving memory, reducing anxiety, and treating epilepsy. A class of powerful compounds called bacosides in Bacopa monnieri is believed to be responsible for these benefits.
Common Dosage: The recommended dosage for Bacopa Monnieri is 300 mg to 450 mg per day.
EPIMEDIUM EXTRACT:
Origin: An herb native to China
Also Known As: Horny goat weed
Overview: Epimedium is better known as Horny Goat Weed and is used for weak back and knees, joint pain, osteoarthritis, mental and physical fatigue, memory loss, high blood pressure, heart disease, bronchitis, liver disease, HIV/AIDS, polio, a blood disorder called chronic leukopenia, viral infections of the heart, bone loss after menopause, weak bones (osteoporosis), and as a tonic. Epimedium is also used to help improve sexual performance and is used to help arouse sexual desire.
Common Dosage: 180 mg to 900 mg for post-menopausal women and 900 mg to 1,500 mg for most adult men.
RHODIOLA ROSEA ROOT POWDER:
Origin: Roots of the Rhodiola Rosea plant
Also Known As: Golden root, Rose root, Aaron’s rod, Arctic root, king’s crow
Overview: Rhodiola Rosea is an adaptogenic herb that helps the body adapt to various stress including physical, chemical, and environmental. It is known for its fat-burning, energy-enhancing and brain-boosting capabilities.
This herb may have several benefits for building muscle, including boosting energy, normalizing hormonal levels, increasing endurance and improving the body’s response to stress. Rhodiola Rosea can also be a useful tool for boosting performance and helping your body cope with the physical stress of training.
Common Dosage: The recommended dosage for Rhodiola depends on several factors such as the user’s age, health and reason for supplementing with the extract. For addressing symptoms of stress, the recommended dose is 400 to 600 mg per day. Meanwhile, for enhancing athletic performance, the recommended dose is 200 to 300 mg one to two hours prior to a workout.
ALOE FEROX EXTRACT:
Origin: Derived from the Aloe ferox plant indigenous to southern Africa
Also Known As: Bitter aloe, Cape aloe, Red Aloe,Tap Aloe
Overview: Aloe ferox is a single-stemmed succulent evergreen that is often used to make the purgative medication called bitter aloe. Its sap contains the compound anthraquinone which is used as a laxative. It can also produce a non-bitter gel which is often used in cosmetics.
Common Dosage: Currently there is no standard dosage for Aloe ferox.
ALPHA LIPOIC ACID :
Origin: Naturally-occuring in the body but can be sourced from supplements and food such as spinach, broccoli, yams, potatoes, yeast, tomatoes, Brussels sprouts, carrots, beets, ruce bran, and organ meat.
Also Known As: Thioctic acid,6,8-Dithiooctanoic acid
Overview: Alpha Lipoic Acid is a vitamin like chemical called an antioxidant. Alpha Lipoic Acid is used for diabetes and nerve related symptoms of diabetes. This compound seems to help prevent certain kinds of cell damage within the body and also restores vitamin levels such as Vitamin E and Vitamin C. It is also used to break down carbohydrates and to make energy for the other organs within the body.
Common Dosage: The recommended dosage for Alpha Lipoic Acid is 100mg-400mg daily.
GINKGO BILOBA POWDER:
Origin: Derived from the Gingko Biloba tree native to China
Also Known As: Ginko, Maidenhair Tree
Overview: Ginkgo Biloba originates from the leaves of the Ginkgo Biloba tree and have been used in common treatment in Chinese Medicine. Ginkgo Biloba improves blood flow to the brain and acts as an antioxidant. These effects may translate into some benefits for certain medical problems. Studies have also found that in healthy people, ginkgo might modestly boost memory and cognitive speed. Ginkgo Biloba studies have shown that it can help with memory problems caused by dementia or Alzheimer’s disease.
Common Dosage: The recommended dosage for Ginkgo Biloba is 120 mg to 600 mg daily in healthy individuals.
GREEN TEA EXTRACT:
Origin: Derived by soaking tea leaves in an alcohol solution
Also Known As: Camelia sinensis
Overview: Green Tea Extract comes from the Camellia Sinensis Plant. Green Tea Extract is used to improve mental alertness and thinking as well as being used for weight loss and to treat stomach disorders, vomiting, diarrhea, headaches, bone loss, and solid tumor cancers. Green Tea Extract contains 2% to 4% caffeine, which affects thinking and alertness, increases urine output, and may improve the function of brain messengers important in Parkinson’s disease. Caffeine is thought to stimulate the nervous system, heart, and muscles by increasing the release of certain chemicals in the brain called neurotransmitters.
Common Dosage: The recommended dosage for Green Tea Extract is 200mg daily in healthy individuals.
L-CARNOSINE:
Origin: Classified as a dipeptide, L-carnosine is a combination of two amino acids, in this case alanine and histidine. It naturally occurs in high concentrations in skeletal muscle tissue, and therefore may support muscle vitality. L-Carnosine is also an antioxidant that stabilizes cellular membranes, protecting them from damage by free radicals. Because L-carnosine is only found in vertebrates, it is especially important for persons who do not consume beef, pork or chicken.
Also known as: beta-alanine and L-histidine
Overview: Carnosine is a compound made up of two amino acids (beta-alanine and L-histidine) with powerful anti-aging properties. Although carnosine occurs naturally in our bodies, levels decline with age. This makes supplementation an essential part of your whole-body health program.
Common dosage: The recommended dosage for L-carnosine is 300 mg daily in healthy individuals.
L-CITRULLINE:
Origin: The human body, supplements, or food such as watermelon
Also Known As: Citrulline
Overview: L-Citrulline is a naturally-occuring amino acid. The body changes L-citrulline into another amino acid called L-arginine as well as to nitric oxide. It may help increase the supply of ingredients the body needs to making certain proteins. It might also help open up veins and arteries to improve blood flow and reduce blood pressure. L-Citrulline is predominantly used to increase energy, improve athletic performance, reduce muscle weakness, and help eliminate fatigue.
Common Dosage: Up to 9 grams daily
L-LEUCINE:
Origin: Supplements or food such as cheese, soy beans, beef, chicken, pork, nuts, seeds, fish and seafood, and beans
Also Known As: Leucine
Overview: L-Leucine is an essential branched-chain amino acid (BCAA) that is broken down in fat structures. It helps preserve lean muscle mass and maintain nitrogen balance in the body. It also supplies the body with sufficient energy in times of duress such as intensive while also preserving glycogen levels in the muscles.
Common Dosage: 2000 to 5000 mg
COENZYME Q10:
Origin: Produced by the human body but can be sourced through supplements or food such as organ meats, muscle meats, fatty fish, spinach, cauliflower, broccoli, oranges, strawberries, legumes, nuts and seeds, and soybean oil.
Also Known As: 39-Decamethyltetraconta-2, Ubiquinol, CoQ10.
Overview: Coenzyme Q10, shortened to CoQ10 is a substance found in all of the cells within the body. It is used to produce energy your body needs for cell growth and maintenance. CoQ10 is said to help heart failure, muscular dystrophy, and is said to boost energy and speed up recovery for strenuous exercise.
Common Dosage: The recommended dosage of CoQ10 is 100mg daily.
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